Publications

 

 

  • Antiviral Innate Immunity

    • Jhih-Pu Lin, Yu-Kuan Fan, and Helene Minyi Liu, "The 14-3-3η Chaperone Protein Promotes Antiviral Innate Immunity via Facilitating MDA5 Oligomerization and Intracellular Redistribution". PLoS Pathogens. 2019 Feb: 15(2): e1007582. https://doi.org/10.1371/journal.ppat.1007582

    • Hao-Sen Chiang and Helene Minyi Liu, “The Molecular Basis of Viral Inhibition of IRF- and STAT-Dependent Immune Responses.” Frontiers in Immunology. 2019 Jan:9:3086. doi: 10.3389/fimmu.2018.03086

    • Helene Minyi Liu, Fuguo Jiang, Yueh Ming Loo, ShuZhen Hsu, Tien-Ying Hsiang, Joseph Marcotrigiano, and Michael Gale Jr. “Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by The Histone Deacetylase 6.” EbioMedicine, 2016 Jul; 9: 195–206.

    • Rei-Lin Kuo, Zong-Hua Li, Li-Hsin Li, Kuo-Ming Lee, Ee-Hong Tam, Helene Minyi Liu, Hao-Ping Liu, Shin-Ru Shih, and Chih-Ching Wu. “Interactome Analysis of the NS1 Protein Encoded by Influenza A H1N1 Virus Reveals a Positive Regulatory Role of Host Protein PRP19 in Viral Replication.” J. Proteome Res., 2016, 15 (5), pp 1639–48

    • Helene Minyi Liu, Yueh-Ming Loo, Stacy M. Horner, Gregory A. Zornetzer, Michael G. Katze, and Michael Gale Jr. “The Mitochondrial Targeting Chaperone 14-3-3ε Regulates a RIG-I Translocon that Mediates Membrane Association and Innate Antiviral Immunity.” Cell Host Microbe, 2012. 11(5): p. 528-37
      Helene Minyi Liu, Michael Gale Jr.. “ZAPS electrifies RIG-I signaling.” Nat Immunol, 2011. 12(1): p. 11-2.

    • Stacy M. Horner, Helene Minyi Liu, Hae Soo Park, Jessica Briley, and Michael Gale, Jr.. “Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus.” Proc Natl Acad Sci U S A, 2011. 108(35): p. 14590-5.

    • Helene Minyi Liu, Michael Gale Jr.. “Hepatitis C Virus Regulation of Interferon Antiviral Defences.” In Karen Mossman, Viruses and Interferon: Current Research (pp.215-234). Caister Academic Press (2010).

    • Helene Minyi Liu, Michael Gale Jr.. “Hepatitis C virus Evasion from RIG-I-dependent Hepatic Innate Immunity.” Review, Gastroenterol Res Pract, 2010. 2010: p. 548390
       

  • HCV Replication and HCV Pathogenesis

    • Linya Wang, Ja Yeon Kim, Helene Minyi Liu, Michael M. C. Lai, and Jing-hsiung James Ou, "HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication." PLoS Pathog, 2017. 13(9): e1006609

    • Helene Minyi Liu, Hideki Aizaki, Keigo Machida, J.-H. James Ou, Michael M. C. Lai; “Hepatitis C Virus Translation Preferentially Depends on Active RNA Replication.” PLoS One, 2012. 7(8): p. e43600

    • Donna Sir, Jeff Cheng-fu Kuo, Yongjun Tian, Helene Minyi Liu, Keigo Machida, Michael M.C. Lai, and Jing-hsiung James Ou “Replication of hepatitis C virus RNA on autophagosomal membranes." J Biol Chem, 2012. 287(22): p. 18036-43

    • Helene Minyi Liu, Hideki Aizaki, Keum S. Choi, James J.-H. Ou, and Michael M.C. Lai. “SYNCRIP (Synaptotagmin-Binding, Cytoplasmic RNA-Interacting Protein) is a host factor involved in Hepatitis C virus RNA replication.” Virology, 2009. 386(2): p. 249-56.

    • Keigo Machida, Hidekazu Tsukamoto, Hasmik Mkrtchyan, Alla Dynnyk, Helene Minyi Liu, Sonja Hess, Raymond Deshaies, Sugantha Govindarajan, Ratna Ray, Jing-Hsiung Ou, and Michael Lai. “Toll-Like Receptor 4 Mediates Synergism between Alcohol and HCV in hepatocellular Carcinoma: The Role of Stem Cell Marker Nanog.” Proc Natl Acad Sci U S A, 2009. 106(5): p. 1548-53.

    • Yasuteru Kondo, Keigo Machida, Helene Minyi Liu, Yoshiyuki Ueno, Koju Kobayashi, Takaji Wakita, Tooru Shimosegawa, Michael M Lai. “Hepatitis C virus infection of T cells inhibits proliferation and enhances FAS-mediated apoptosis of T cells by down-regulating CD44v6 expression.” J Infect Dis, 2009. 199(5): p. 726-36.

    • Hideki Aizaki, Keum Choi, Minyi Liu, Yi-Jia Li, Michael Lai. “Polypyrimidine-tract-binding Protein is a Component of the HCV RNA Replication Complex and Necessary for RNA Synthesis.” J Biomed Sci, 2006. 13(4): p. 469-80.

    • Yasuteru Kondo, Vicky M H Sung, Keigo Machida, Minyi Liu, Michael M. C. Lai. “Hepatitis C virus infects T cells and affects interferon-gamma signaling in T cell lines.” Virology, 2007. 361(1): p. 161-73.

    • Itsuki Hamamoto, Yorihiro Nishimura, Toru Okamoto, Hideki Aizaki, Minyi Liu, Yoshio Mori, Takayuki Abe, Tetsuro Suzuki, Michael M. C. Lai, Tatsuo Miyamura, Kohji Moriishi, Yoshiharu Matsuura. “Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B.” J Virol, 2005. 79(21): p. 13473-82.

Last update: 2020/10/20 by HML